Sensitivity Case-Control Regression Analyses Corresponding to the Table and eTable 10, Using Only Samples From Cohorts With a Given Ascertainment DesignĮTable 11. Sensitivity Case-Control Regression Analyses Corresponding to the Table Additionally Adjusting for Pathology Verification StatusĮTable 10. Sensitivity Case-Control Regression Analyses Corresponding to the Table Using Clinically Determined Phenotypes OnlyĮTable 9. Case-Control Regression Results Across APOE Dosages and Strata for Hispanic Individuals (HISP), Stratified Into Hispanic Whites (HW) and Hispanic Blacks (HB)ĮTable 8. Case-Control Regression Results Across APOE Strata Corresponding to Figure 1aĮTable 7. Overview of Participant Demographics and Ascertainment Design Across CohortsĮTable 6. Overview of Participant Demographics Across the Cohort-Platform Technical CovariateĮTable 5. Overview of Participant Demographics Across Race and Ethnicity and APOE Genotype StrataĮTable 4. Overview of ADSP Studies With WES or WGS Available Through NIAGADS DSS (NG00067)ĮTable 3. Overview of Genotyping Platforms Across All Available AD-Related Genetic DataĮTable 2. Survival Analyses Results, Through Cox Regression, Across APOE Genotypes, for Non-Hispanic White (NHW), Non-Hispanic Black (NHB), and Hispanic (HISP) IndividualsĮTable 1. Sex-and-Age Stratified Results for APOE Genotype Case-Control Regression Analyses Across Non-Hispanic White (NHW), Non-Hispanic Black (NHB), and Hispanic (HISP) IndividualsĮFigure 5. APOE*34-by-Sex Interaction Effect in Case-Control Regression Analyses for Individuals 60 to 70 Years of Age Is Preserved Across Sensitivity AnalysesĮFigure 6. Alternative Visualizations of Case-Control Regression Results Presented in Figure 1ĮFigure 4. Admixture Plots Across the Five Major Super Populations, for Participants Included in Association AnalysesĮFigure 3. Flowchart of Sample/Participant Filtering for APOE Association Analyses With Alzheimer Disease RiskĮFigure 2.

What does a high genetic variance mean